Anonymous3: yes if you would have beat the game a second time it basicley says she was different "from birth" thats why granny had to take her in. stop lookin at retarded websites and just play the damn game
Anonymous4: Original human Kaine who lived in 21 century (and then became gestalt (also known as shade) to 1st NieR events) is 100% female with vagina. Replicant Kaine (her clone but with own personality) was born hermaphrodite due program error. Despite having male genitals replicant Kaine still have female consciousness and body (and she actually hates the fact she has dick).
She's a tranny
According to the game's mythology, demons are in the practice of growing a penis during possession, as that's how Kainé was presented with such.